Proverbs provides moral instructions on how to live according to Godly wisdom. It is a contrast of a foolish person who ignores God and a wise person who loves God and applies His wisdom to life. Folly (gossip, pride, lust, fear, dishonesty, arrogance, deceit, etc.) is everything opposite of wisdom (faithful, moral, trustworthy, hopeful, humble, self-control, integrity, etc.).
Folly (on the left with dark colors) and wisdom (on the right with yellows and golds representing God) intertwine in the middle. Blue and gold threads gradually make their way into the hearts of the two people in the painting.